Le-heng Wang             Product Manager & Software Engineer       Bioinformatics Group, Institute of Computing Technology, Chinese Academy of Sciences.

Correspondence

Research Interest

• Bioinformatics (mass spectrometry-based computational proteomics)
• Artificial Intelligence
• Software Engineering

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Project

pFind : a software package for peptide and protein identification via tandem mass spectrometry. (Paper / Web / Google)

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Publications

• Chen Zhou, Hao Chi, Le-Heng Wang, You Li, Yan-Jie Wu, Yan Fu, Rui-Xiang Sun, Si-Min He. Speeding up tandem mass spectrometry-based database searching by longest common prefix. BMC Bioinformatics, 2010, 11:577. (Abstract / (Full Text)
• Le-heng Wang, Wenping Wang, Hao Chi, Yanjie Wu, You Li, Yan Fu, Chen Zhou, Ruixiang Sun, Haipeng Wang, Chao Liu, Zuofei Yuan, Liyun Xiu, Si-Min He. An efficient parallelization of phosphorylated peptide and protein identification. Rapid Communications in Mass Spectrometry (RCMS), 24(12):1791 - 1798, 2010. (Abstract / Full Text)
• You Li, Hao Chi, Le-Heng Wang, Hai-Peng Wang, Yan Fu, Zuo-Fei Yuan, Su-Jun Li, Yan-Sheng Liu, Rui-Xiang Sun, Rong Zeng, Si-Min He. Speeding up tandem mass spectrometry based database searching by peptide and spectrum indexing. Rapid Communications in Mass Spectrometry (RCMS), 24:807 - 814, 2010. (Abstract) / (Full Text)
• SONG LiNa, WANG JingLan, LIU JinFeng, LU Zhuang, SUI ShaoHui, JIA Wei, YANG Bing, CHI Hao, WANG LeHeng, HE SiMin, YU WenFeng, MENG LingYan, CHEn Shuo, PENG Xu, LIANG YiMin, CAI Yun, and QIAN XIaoHong. N-glycosylation proteome of endoplasmic reticulum in mouse liver by ConA affinity chromatography coupled with LTQ-FT mass spectrometry. SCIENCE CHINA Chemistry, 4:768-777, 2010
• Yan Fu, Simin He, Ruixiang Sun, Le-heng Wang. A review of Key computational problems in tandem mass spectrometry-based protein identification. Information Technology Letter. 2010. (in Chinese)
• Wei Jia, Zhuang Lu, Yan Fu, Hai-Peng Wang, Le-heng Wang, Hao Chi, Zuo-Fei Yuan, Zhao-Bin Zheng, Li-Na Song, Huan-Huan Han, Yi-Min Liang, Jing-Lan Wang, Yun Cai, Yu-Kui Zhang, Yu-Lin Deng, Wan-Tao Ying, Si-Min He, and Xiao-Hong Qian. A Strategy for Precise and Large-Scale Identification of Core Fucosylated Glycoproteins. Molecular & Cellular Proteomics, 8:913-923, 2009.(Abstract / Full Text)
• Yan Fu, Wei Jia, Zhuang Lu, Haipeng Wang, Zuofei Yuan, Hao Chi, You Li, Liyun Xiu, Wenping Wang, Chao Liu, Le-heng Wang, Ruixiang Sun, Wen Gao, Xiaohong Qian, Si-Min He. Efficient discovery of abundant post-translational modifications and spectral pairs using peptide mass and retention time differences. Accepted by APBC 2009, BMC Bioinformatics, 10(Suppl 1): S50, 2009. (Abstract / Full Text)
• Le-heng Wang, De-Quan Li, Yan Fu, Hai-Peng Wang, Jing-Fen Zhang, Zuo-Fei Yuan, Rui-Xiang Sun, Rong Zeng, Si-Min He and Wen Gao. pFind 2.0: a software package for peptide and protein identification via tandem mass spectrometry. Rapid Communications in Mass Spectrometry (RCMS) Vol.21, No.18, pp2985-2991, 2007. (Abstract / Full Text / Supplementary information)
• Cui Zou, Yan Fu, Ruixiang Sun, Le-heng Wang, Debin Zhao. pPre_ITMS: Tandem mass spectra preprocessing system based on machine learning. Computer Engineering and Design 07-28-09, 2007. (in Chinese)
• JinJin Cai, JieYu Zhao, Le-heng Wang. AproPhos: Protein Phosphorylation Prediction Based on AdaBoost. Microelectronics & Computer 07-0035-05, 2007. (in Chinese)

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Technical Reports

• Lessons from our engineering practice.ppt.(ppt) (in Chinese)
• The software engineering and architecture of pFind protein identification system.(pdf) (in Chinese)

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Hobby

reading, rock'n'roll, whodunit, skating on wheels, skiing, travelling, soccer

my website about linux kernel: http://joyfire.net

my blog in Chinese: http://wangleheng.net

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Last Modified:  September 20, 2011